Have you thought about a deathcage match? Last person standing is right?
I voted yes in the poll simply because, of the settings currently available, most are tied to a specific genre and these genres more often than not don't quite fit the new edition. Yes they can be adapted and will be as WotC releases them on an annual basis. Most people have a concept of D&D and many don't see certain settings as fitting that concept.
For example, myself:
Greyhawk; when I started playing this was the setting as in the only setting.
Dragonlance; it didn’t click for me, draconians, tinker gnomes and it had kender.
Forgotten Realms; this was the setting for me, it just clicked with my D&D concept.
Kara-Tur, Maztica and Al-Qadim; although technically a part of the FR, not my cup o' tea.
Dark Sun; Mad Max with magic and psionics, definitely not my concept.
Ravenloft; I played Call of Cthulhu for horror, but Ravenloft was more gothic and I liked it.
Birthright; I prefer the small adventuring party as opposed to nation ruling.
Council of Worms; again not my concept.
Mystara; even though we played a majority of the modules we adapted them to AD&D rules.
Planescape; too much intrigue and not my concept.
Spelljammer; I don’t know why I liked this so much, it just clicked with me.
Eberron; magi-tech, warforged, not my concept.
PoL; I kind of like the fact that all those locations from classic modules show up here. Would like to see maps and support for it.
New setting; I see a setting that has elements of western and eastern cultures as well as varying levels of civilization. A place where the Paladins Code and Bushido both are valid.
Bel