Well, I know for me, among other things, one of the things that turned me off to 4e was that it didn't feel "innovative" so much as it felt "calculated."
To me, much of the rule system felt like it was put in place not because it was the "best," or most "innovative" evolution of d20, or PnP RPGs, or because it was really going to provide a better role-playing experience. It seemed like a lot of 4e was put in place because it fit into the best "marketing scheme" for WotC. Emphasis on minis (cash cow), easier to build a digital interface for (DDI and subscription revenue streams), trying to capture the MMO crowd, the new artwork for a younger audience, the "Emo" dragonborn and tiefling races.......as a whole it all just had this calculated, sterile, corporate marketing-department feel to the whole production.
Paizo as a company, and most of their product feels the exact opposite to me. Certainly, they're trying to make money, but not at the expense of quality production. It's not innovative from a mechanics standpoint, but from the standpoint of creating a quality experience, they are definitely innovative. They grasp like no other current RPG company how to meld the elements of a fantasy RPG adventure into a sum that is greater than its parts, particularly in their adventure paths. But if at some point they get big enough to start acting "corporate," I'll likely abandon my loyalty to them as well.