I got the game a few days ago and have been playing it a bit. The game's a lot of fun; here are my thoughts.
+ I'm not very far in the game (4 hours?) but I've been enjoying the story so far. The NPCs are interesting and I love watching turmoil build in my slowly-growing party. A lot of plot threads are being laid out, and I'm curious to see where they go. The way the dailog and conversation camera is handled makes the game feel a lot like Knights of the Old Republic (this is good). Plus there's good lip synching. I could never get into the original NWN because the story didn't work for me; I'm happy the opposite is true for the sequal.
+ Lots of game-mechanics-related character customization. Lots of prestige classes (and the Eldritch Knight and Arcane Trickster, yay!), one new core class (the warlock), and lots of feats (practiced spellcaster is an important addition, since it makes multiclassed spellcasters much more viable). You can also choose your deity and character background . . . wondering how these will be referenced in game.
+ Solid gameplay. Combat is fun, and you get a fair amount of choices in how to handle some encounters. There seem to be a lot of side quests too.
- Not so much aestetic character customization. You get a few different heads and hair styles, can can change eye color / hair color / skin tone. I found the choice of colors limiting . . . I wanted my character to have bright-red hair, but could only get a rusty brown. Plus the characters just don't look as cool as they ought to.
- Performance. This is a big one, and I think gamespot knocking the game's graphics is perfectly justifiable. I've had to make some major concessions in the lighting / shadows deparment to get this to run at a fair frame rate (like around 15 fps, according to the ingame display). Even then it fluctuates a lot, especially when there are several NPCs on the screen. My PC ran Oblivion pretty well, and Guild Wars perfectly . . . it's not that NWN 2 isn't in the same ballpark as these games, it feels like its not even playing the same sport. This also means my friends with average PCs won't be able to join in multiplayer. I really hope Obsidian fixes this in later patches.
(My specs: 4 ghz Intell 4 processor, GeForce 6800, 1 gig RAM)
In the end, NWN2 is a lot of fun and its shaping up to be an excellent RPG, but you need a serious gaming computer to run it. If you're on the fence about getting it, you should probably wait until its properly patched or you can upgrade.
Edit: Wow, turning off shadows entirely makes a huge improvement!