I think that Neth, "The Plane That Lives", is more an example of what is possible to do, and less "This is an awesome plot hook that everyone should use".
With that said, I'd love to incorporate Neth in a planar hopping campaign. If I remember correctly, Neth is curious and seeks some form of interaction with visitors. Been a little while since I read up. It could be a neat 'Jonah in the belly of the whale' experience, where characters are stuck for a day while the caster has to wait a day to prepare another Plane Shift spell or something. They make it out alive, but reeeeally yucky.