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(Photo credit: sciencenews.com)
E Muscae is a fungus that infects flies and always kills them at sundown. The infected fly climbs a high plant and glues its mouthparts to the stem. Then at sundown it opens its wings and dies.
There's a theory that the fungus always kills at sundown so that it can start producing spores at night and avoid the heat of the day.
In a D&D campaign, there could be a necrotic fungus that is dormant during the day, but at night turns people into ravenous zombies! The characters have to figure out how to avoid killing their infected friends and friendly NPCs and find a cure (or the source) of this fungus.
I love the idea of a town full of friendly folk who suddenly sprout mushrooms from their heads and go on killing rampages at night, then wake with no memories. "Huh, I wonder where those travelers went... They were so friendly (burrrp)."