Truthfully the RPG items they could put out that I'd like to see aren't the TSR ones. Avalon Hill is under the WotC umbrella, and they had Runequest 3rd edition. I'm indifferent to the rules, but the supplements like Shadows on the Borderlands, Dorastor, Strangers in Prax, Sun County and others would absolutely go onto my Must Buy list.
Chaosium owns the rights again. They have said they had plans for RQ3 PDFs. IIRC. But with as long as it took for the 2E versions, I wouldn't hold my breath.
I'd like to see someone pick up SPI's Dragonquest (and do a proper 3rd edition, not the TSR neutered 3rd edition)