Other posters have already made good predictions. I'd like to add to that, that I do not think we'll likely see a lot of physical published material outside of the already semi-confirmed adventure paths and player options to go with them, I'm afraid. I too expect a good OGL and I do expect the trend of material being out-sourced to 3rd parties (like they are doing with the Elemental Evil adventure path) to continue.
I think online we will see some basic initial support by WotC for the other settings, like stats for the warforged race of Eberron or maybe an article or two with basic psionics for Dark Sun. As well as at least some more news on what to expect in the future. I am not sure if we are actually going to get a Campaign Guide for Forgotten Realms or the other settings, but I do hope so very much.
Considering the next non-adventure path book with player's options, I am not sure, I expect WotC to be hesitant with books covering things like Psionics as it really is a hit or a miss and they need to get it well, maybe even releasing another playtest for material like that, so we'll likely first see a lot of smaller and safer, optional alternative rules.