So, a few things in Round 2. To start, readying an action doesn't consume your reaction until you use your reaction. In essence, the Ready action creates a new trigger where you can use your reaction to take the specified action. It does not, however, remove other triggers. You can still opt to use your reaction to take an opportunity attack (if you meet the conditions) or cast a spell that is a reaction, like shield. Doing so, though, will cause the held spell to be wasted, because you then won't be able to use it prior to your next turn, and it will be lost.
The second thing is the "sneaks in and attacks." This requires a very special set of battlefield terrain or features OR an extremely lenient ruling by the GM. In combat, you are assumed to be looking for threats, and you cannot hide if you can be seen clearly. Given there is no facing, the moment a hidden enemy enters a clear space where they can be seen, they are no longer hidden from those that can see them. There isn't, in the rules, any grace space or distance for this, although you can rule otherwise. Now, battlefield terrain, like tall grass everywhere, can let a hidden enemy sneak up to a target, as can things like fog or darkness, but, in general, it's uncommon that a hidden enemy will be able to sneak all the way up to a target.