The Pieces:
Here's another prediction: The three pieces (of which Kal-El acquired one... if Clark remembers that) point to the mentioned-in-this-episode place of knowledge, which Supes will someday find in Alaska/Antarctica, and name The also-mentioned-in-this-episode Fortress of Solitude. There he will find the Kryptonian computer-equivalent thingamabob with the personality of his Kryptonian Mother (what's her name? Laura?) within it.
The only cure to a Father's will is a Mother's love.
Y'hafta love the way that Smallville keeps dropping "hints". Chloe telling Clark that he looks good in blue... Clark running around the hospital in a red... blanket... Lois' stating that she prefers nerds in glasses... Now where're the telephone booths, in Smallville?
I still say that Lana will be killed off, in some fashion. Again, we'll see!
Kristen Kreuk (the actress who plays her) has been aired all over the WB as saying that she wants to play more of a vixen... Doesn't surprise me, then, that she's been "possessed" by another personality, so that she can let the beast out...
And, of course, since she has already been infected with green kryptonite (wearing a piece around her neck throughout the first season), and has already displayed powers (becoming precognitive after the gas main blew up), she is a super-powered vessel for her warrior-maiden possesser.
Yup; she's doomed! ;-p