A Human could make a good Barbarian/Runepriest too.
With the Extra Feat you can have your Hybrid Talent option and weapon proficiency at lvl 1. And an extra at will for the Hybrid is the bees knees.
Your CON is going to be 16, and that is a bummer but the payoff is interesting as you gain versatility and access to your needed feats faster.
As for Devastating Strike... don't really rate it. Howling Strike is better. Charge becomes your bread and butter, which apart from the extra damage and the magic item support (which is brutal) is more accurate.
But you don't open with howling strike.
In your model, you're opening with howling strike, and then... what... more howling strike? You're not fulfilling the role as a leader.
In my model, you're opening with Word of Diminishment. This assigns them vulnerability 2 (at heroic) which then gives them Vulnerability 2. Then you make that beefy 1[W]+1d8+2+Str... and if you get hit +Con...
You don't mind getting hit, but you don't want to get rained on all the time, surely. Rageblood vigor only gives you temporary hp when you kill something, so not that often. With the third at-will you could take Recuperating Strike if you wanted Temp HP at will, but I'd probably choose Word of Shielding for some more Leader Options or Howl of Fury for a touch of Minion control at-will.
I like Howl of Fury. I'd use it to kill a minion to get those temp hp. Save those minions for when they can save you!
I'd go with Runepriest Armour Proficiency as my hybrid talent option, personally. I don't like being hit, temp. hps or not. And I'd get Fullblade Prof. for the extra accuracy, which makes up for 18 STR and surpasses it when you charge with Howling Strike. Your going to want a Vanguard Weapon, Badge of the Beserker and a Horned Helm.
But if you're charging a lot, you -want- rageblood vigor! They go hand in hand. You're wielding a two-handed weapon, so the extra shield is not a bonus. You -have- the prerequisites for chainmail, so you gain NOTHING by pissing away your hybrid option on this.
Heck, if you really didn't want to be hit, you could use a Bastard sword and light shield or train in an Urgosh to get your AC up to 18 at level 1. Then put 16 in WIS and 13 in CON and take the Defiant Word option instead. Extra damage when you are missed. Plus you could have Impultur as your Background (which uses WIS to calculate your HP, or even Auspicious Birth, and calculate HP using STR) to avoid the lowering of your HP, and you'd gain a very nice bonus to your Perception, Insight and Nature skills.
Bastard Sword + Shield = You never get to use a Barbarian Power. All of the ones worth taking have the disadvantage 'Must use a two handed weapon.'
That said, Urgosh does allow you to raise your AC. But this is not a defensive build. If you want Moar Defenses, get Scale Armor. Wisdom doesn't help a barbarian.
I get your build, but this is its problem in a nutshell:
1) You're NOT afraid to get hit. Barbarian/Runepriests can -handle- getting hit inherently. If incoming damage is a problem, Word of Diminishment ALSO has your back. Remember: With -every- Runepriest power, you get -two- powers, not just one.
2) You're concentrating on charges but then you're castrating yourself by being defensive and NOT taking Feral Might. I like the idea in general, but gonna do it, DO it.
3) You're suggesting a shield for a Barbarian. The power of Barbarians are in having both hands full of death. What you're suggesting sounds more like a viable build for a Fighter/Cleric. Which, by the way, is a good build.
All that said, I -do- like the idea of going Human at first level. Word of Shielding is -very- good too.