I ran a serious gamma world campaign back in the early 1980's, but I've got no idea whether or not that could be done with these new rules in the same way - so much derives from the crunch in the game.
Let me ask you this question in response: is the world of Bas-Lag not gonzo?

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.