I second Numenera. Also, no one has mentioned Draw Steel yet. While it is getting some attention, it doesn't seem like enough considering how well their Kickstarter did. And as far as covering D&D (even as an April Fool's joke), why not cover it using the Level Up ruleset. Certainly that hasn't gotten as much attention as it should.
As a side note: That can be a Pod cast too; covering alternate rulesets or campaigns of D&D.