In 3e, it would have mattered (given all the various abilities that were alignment-dependent, like holy, smite etc).
But considering that there are no effects in 4e keyed off alignment, it doesn't really matter to me what the alignment of my foe is, so long as the can justify why we have to fight a LG foe (assuming we are a good party).
But considering that there are no effects in 4e keyed off alignment, it doesn't really matter to me what the alignment of my foe is, so long as the can justify why we have to fight a LG foe (assuming we are a good party).