I am, generally, not a fan of anime or the manga style, whichever you prefer. Mostly as a combination of Joshua Dyal and jgbrowning's viewpoints. It's not so much that I flat out dislike the artwork (or some of it, at least... for instance, I like my people to have noses, rather than a little microscopic corner in the middle of their face, thankyouverymuch) as it is that I'm not fond of the way it is often animated (with the monstrous changes in mouth/eye size, and whatnot; and yes, I realize these types of things are usually used as comedic devices), and I associate them with a lot of very thinly plotted material.
Now, I say this as the brother of a pretty big anime fan who has tried to make me see the error of my ways and convert me with the best in his arsenal. And I've still never been impressed with the scripts.
Back to the art, I find the complete and utter lack of attention to human proportion disturbing. It's neither pleasant, nor inspires the young artist to learn such things, which locks them out of ever trying different styles in the future, which I think has probably spoiled budding talent left and right. I'm also not impressed by such small details like all the people portrayed in anime look essentially the same, with the same shaped heads, the same massive breasts, and the same oversized eyes. Character differentiation, as far as I can tell, is primarily via the exact lay of the spikey hair and the clothing, cause lord knows you couldn't tell the faces apart by themselves.
Of course, I also (and this may be the biggest strike against it) am downright sick of it! Everywhere I look, anime is being thust upon me, and there are five kajillion and one (bad) amateurs who have discovered the internet and apparently think they're the hottest thing since the toaster oven.
I'll point to Elfwood as an example. When I first discovered it back in the mid-90's, I loved just browsing through it, enjoying the diversity in style and subject. The last time I bothered looking at it was a year or two ago, and all it was anymore was anime this, anime that. So maybe I'm jaded towards the style because it's taken all of the good talent that used to divvy itself up between comic-style art, realism, etc. and funnelled it into one monotonous genre.
For the record, so nobody thinks I'm singling anything out, I'm also dead sick of lens-flared Photoshopped color art.
Oh yeah, and what's with the elves who can't walk through doors because of their horizontally growing ears?