Ravenous Bugblatter Beast of Traal
I've only given S&V a skim, haven't had a chance to play, so please correct me if I have anything incorrect.Interesting. I haven't played (or even read) BitD, but I have played in a full campaign of Scum & Villainy. And we didn't find it difficult to switch out the setting for one of our own making.
Now, granted, our setting did need to share some particular things with the book's setting - Precursor artifacts, mystics of the Way, and so on. And part of our worldbuilding was to come up with a similar array of factions up to a variety of goals.
Is that what you're talking about, or is S&V genuinely different from BitD in this respect?
I think one big difference is that S&V setting-wise is more a common amalgamation of several settings such as Star Wars, Cowboy Bebop, Firefly, etc. It's not a common setting, with needing things like The Way, but it's not particularly unique. As you mention, you can fit in the particulars to a variety of settings.
On the other hand the parts of the BitD setting that need to fit in, while individually things you would see elsewhere, are very rarely put together, especially with the twists they put on them. Just like in S&V these are reflected in the playbooks, so you need to have all of them.
If i was going to use a cooking analogy, S&V might require flour, eggs, and milk - something that you can make may recipes out of, while BitD requires pickled cabbage, chocolate, and jalapeno peppers. Individually ingredients that you can use, but when you require them all it really locks down what you can make.
I believe that both the playbooks and the crew sheets are more tightly tied to those particulars as well, but that may be my liited familiarity with S&V saying so. Some like the Mystic have stronger ties, but more of the playbooks felt like they would work in a wide variety of settings.
EDIT: This isn't saying S&V isn't bespoke. This started as disagreement with @Neonchameleon that BitV was easily swappable to other settings, and then just answering a question about how S&V was more swappable. Just being able to change settings isn't a sign that something isn't bespoke.