I never use the ignore option.
There was a time when I thought about it, because a lot of people here on ENWorld annoyed the heck out of me, but then I went to a Gen Con and met a lot of them in person. I liked them well enough. No great new friendships or anything, but it drove home that judging people through a message board is pretty stupid, so I quit doing it.
So now when I get irritated I remind myself of how stupid I am being and do my best to just stay away from whatever thread is annoying me until I am sure I can be rational again. So now there are very few things that will set me off, mostly when something convinces me they are blatantly lying. Even then, I will hopefully refrain from saying anything, I'll just take note that they are probably a liar and take anything they post with a big box of salt.
I would guess I am on some people's ignore list, because I do seem to irritate some people, but I don't care. Their inability to deal with me is their problem, not mine. If we knew each other in person, I would maybe do something about it, but via a message board? Nope. Its a lousy vehicle for communicating opinion anyways.