I think just about anything with the name 'Dungeons & Dragons' on the cover will sell 'well' due to the recognition and value of the brand name.
The better question is if it will sell well enough to meet the expectations of the bean counters.
The new rogue and fighter subclasses being based on basic attacks as opposed to lots of encounter powers and dailies seems a good sign for significant change. System fundamentals will stay firmly the same though. I dunno; could be worth a glance even to people who dislike 4e fundamentally, also might be fun to buy the new Red Box for a younger nephew or cousin or whatever to mirror how a lot people on this site were exposed to D&D.I'm willing to take a look and keep an open mind, but I'm honestly pretty happy with Pathfinder. It would have to be a significant departure to really get me back, and I doubt that's going to happen.
andSystem fundamentals will stay firmly the same though.
I dunno; could be worth a glance even to people who dislike 4e fundamentally...
I think just about anything with the name 'Dungeons & Dragons' on the cover will sell 'well' due to the recognition and value of the brand name. The better question is if it will sell well enough to meet the expectations of the bean counters.

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.