An interesting article appeared on DnDBeyond that address converting D&D to other genres. They cite Eberron and Ravenloft as examples, and I wager it's going to be controversial here.
The link:
Adapting Other Genres to D&D
Some of the cliff notes parts.
* Adapt the genre to D&D, not D&D to the setting.
* Try to limit restrictions for your players, esp to magic and magic items.
* Add rather than subtract options when possible.
* Find where D&D and the genre cross and focus on those.
* If you're genre requires extensive rewriting of the game, consider a better suited RPG.
Thoughts on his suggestions?