The OSR has spoiled me. I never have to leave the OD&D-compatible ecosystem for any reason (except maybe for a Ghostbusters RPG, but I hope to fix that soon myself). Sci-fi? Between X-Plorers, Hulks & Horrors, White Star, and Stars Without Number, I'm spoiled for choice — I never have to touch Star Frontiers or Alternity ever again. Present day? Skyscrapers & Sorcery, Ancient Mysteries & Lost Treasures, White Lies. Early modern? We've got Lamentations of the Flame Princess for 16th century, Miseries & Misfortunes for 17th century, A Ghastly Affair for 18th century, and Engines & Empires for 19th century (and also Freebooters specifically for pirates and a growing laundry-list of Wild West games — Blood & Bullets, Tall Tales BX, Gunslinger…). There's Gangbusters BX, Raiders! of the Lost Artifacts, Mutant Future, Flying Swordsmen, Beyond the Wall, Through Sunken Lands, The Hero's Journey, Wolves of God, and the list goes on. If I liked cyberpunk, I'd probably be aware of an OSR cyberpunk game too, and then I'd have one more reason than I already have for never touching Shadowrun.