Another one: essence/cyberpsychosis/whatever are stupid ideas that don't make sense in Cyberpunk. Not even mentioning problematic implications (I have half of my body surgically constructed, am I less of a human?), it removes a ship of Theseus paradox that is important to cyberpunk as a genre and replaces it with nothing.
The biggest problem with both
Cyberpunk 2020 and
Red regarding the issue of Humanity is that neither one of them did anything interesting with the idea. Save for lowering an attribute attached to certain skills, there was essentially no difference between a character with a Humanity of 3 and a Humanity of 8. For the most part, Humanity was only affected by cybernetics, so even if you were hovering dangerous close to zero, you were save from cyberpsychosis unless someone happened to give you a drug that temporarily lowered you Humanity.
Interface Magazine, the official Cyberpunk 2020 magazine in the 1990s, had an interesting article detailing the personalities of characters based on their Humanity and Cool levels, but from a practical point of view that didn't impact game play in my experience.
I really liked how they handled Humanity and cyberpsychosis in
Cyberpunk Edgerunners on Netflix. Characters like Maine and David were addicted to the cyberware. They were both on a treadmill, getting geared up so they could make more money, and then spending that money on new cyberware so they would have an edge and make more money. But in Edgerunners, cyberware wasn't the only way to take a hit on their humanity. One person tried to force David to go off the deep end by forcing him to endure some particularly violent brain dances. But that isn't a mechanism we see in either 2020 or Red. It would have been nice if characters could regain a little Humanity by displaying empathy or even losing it by being callous.
To Red's credit, they did fix the problematic implications of Humanity loss. Even as a teen, I know I wondered "What about a dude who loses his leg in an accident?" Cyberware designed to restore normal function doesn't cost any Humanity in Cyberpunk Red. If you have a bad ticker and get a mechanical heart or lose an arm in an auto accident, a piece of gear that restores function won't cost any Humanity at all.