It depends how the glass vials are stored, but yes, there could be some risk of breakage. I would have them stored in padded little boxes in a potion bandolier for easy access and to reduce that problem. In settings with more advanced technologies than the Renaissance period, you could potentially have tin-plate vials (1800s) or plastic (
bakelite was invented in 1907). It depends how wide-spread magic usage is in manufacturing and what is the tech level (e.g., stone age, bronze age, iron age, dark ages, medieval, renaissance, pre-industrial, industrial).
For example, are there magically reinforced ceramic vials (pottery kiln-fired) with spells that prevent/protect breakage? If yes, the vials can be lighter weight.