The big missed chance for me here is the lack of Large PC options. Why can't I play an Ogre...?
The biggest gameplay issue with Ogre is they are large (but so is Centaur and Minotaur if they are not PCs). Large PCs would present some challanges I think and the designers don't want them.
FWIW I have played a "Half-Ogre" using "custom lineage" template from Tashas.