Another vote for Eberron: a perfect marriage of heroic fantasy with modern (early 20th-century) sensibilities. Dragons but also warforged. Kings but also nations. Teleportation but also trains. Old-fashioned taverns but also international corporations. Swords but also at least one nation-destroying nuke. It's a D&D world with gnome reporters angling for scoops, half-orc private-eyes and elven femme fatales, dinosaur-riding halflings robbing trains, and yeah, raiding tombs to recover ancient artifacts before the nazis get there first. I love it.
Runner up: Arcana Unearthed. Monte Cook changed up the traditional fantasy setting enough to make it distinctive, while still leaving it unmistakably a D&D setting. I love the cultural emphasis on ceremony and ritual, and the races, classes, and monsters ooze with flavor. Giants are the (playable) dominant race, wise and just, except when they undergo a ritual to become militant and unyielding. The Verrik are simply alien, perceiving the world in different ways than other races. You can play a fey race that can metamorphose into a sprite. Evocative and simply fresh, through and through.