Here are a few more...
It's a Wonderful Life: The "honeymoon" scene when George comes home after saving the Savings & Loan from the Rush. "Welcome Home, Mr. Bailey," the camera pans as he looks at his new bride, the table, the bird roasting over the fire (attached to the phonograph)... and then the *gulp* as he looks at the queen-size bed.
It's a Wonderful Life: The ending scene with the entire town piling into the Baileys' living room.
Camelot: The whole "I wonder what the King is doing tonight" sequence.
Ocean's Eleven: "Check the tape! Does it say 'Bellagio' on the floor?" ... just as the SWAT team is making its way out of the casino and we see Brad Pitt's face.
Independence Day: "Do me one favor... tell my children I love them very much" as Russell, the whacked-out, alien-abducted fighter pilot goes kamikaze into the alien craft toward the end of the movie.
Prince of Egypt: Moses parting the Red Sea... you know it's coming but it still looks incredible.
Return to Me: David Duchovny arrives home after his wife dies at the hospital. He's still covered in blood and in shock. He closes the door and just sinks down, collapsing into a huge, shaking, sobbing mess.
What Dreams May Come: The "paint" world sequence. I especially love Cuba Gooding Jr.'s delivery of... "Are you your arm? Where does your consciousness exist?" "In my brain, I suppose." "Brain is meat, it's an organ... that's not you. Thought is real... physical is the illusion. Pretty wild, huh?"
Now, granted, some of these are, I guess, very HUMAN moments (Return to Me, Camelot, etc.), but the bare humanity with which they're portrayed just gets me.
--The Sigil