I guess, but I can't think of any game I've ever played where one player letting the others win made it more fun. Maybe a cooperative game where players let the other players get a prize instead of them, but a competitive one like D&D? That makes no sense to me.Because you want to have fun (both for you and the players). If you feel like it would increase the fun, for any reason whatsoever, then why not?
BTW, I would do that only on very rare occasions, but I can think of a game where you fudge alot but is still alot of fun, a la Paranoia.
Neither does your comment about Paranoia. Why wouldn't you openly roll kills on clones? That's what they are there for. You have six of them.