Definately 4e. Oh yes. With so little prep time needed for statistics and a good system in place for skill checks, I can devote more time to the important things- determining plot and putting together exiting encounters (harder now than ever with so little free time). Plus the skill system/lack of magic means that I can generate skill-based checks with at least a passing chance that most characters would be able to participate. I haven't run into any problems with 'what happens when...' either- the skills system tends to cover that nicely.
Finally, it must be said that the martial options means that I can run a low-magic campaign with little or no adaption (as opposed to the 50+ pages of rules that I had for my 3.5e campaign).
I would consider running 3e using a low technology version of the Saga rules (I think there are one of two floating around) since I like the freedom in character generation and the narrative feel. Even then I would apply the 4e monster creation rules to speed things up. Otherwise, no.
One thing I would not do is run a campaign with 4e published adventures though...far too grindy. Decrease the combats, up the threat level and lower the hit points, I say.