As long as the other people at the table are cool with whatever "mature" content is going on, i don't see the harm in exploring the gritty, the gory, the lewd, or the insane.
I will confess that most of my players prefer grit and gore over bump and grind, but that's not always the case. While prepping for a BESM D20 campaign, a player even asked me about the more "mature" side of that genre.
Basically, as long as the material is well written (good ideas for stories, nice adventure hooks, and mechanics that aren't extraneous or encumbering), i'd at least take a look at it. Even if i had to show id to have a look at it.