You won't be terrible as a single class fighter, but you will be a little behind the power curve if you aren't very careful with your feat selection so that they all work together at once. Of course, that's not necessarily a problem as long as you don't play up (LG slang for playing a character in adventures set for higher level characters--for instance playing your 4th level character in the version of a mod designed for 6th level characters (average party level or APL 6)).
So, suggestions:
1. The single classed fighter with a greatsword.
Half-orc
Str 18, Dex 12, Con 16, Int 6, Wis 12, Cha 6 (If you'd rather not be so dumb and uncharismatic, drop the Con to 14 and increase Int or Cha as you desire. You can also drop the dex to 10 without hurting yourself too much).
1. Weapon Focus Greatsword, Power Attack, Cleave
2. Improved Bull Rush
3. Iron Will
4. Weapon Specialization: Greatsword
6. Shock Trooper, Improved Toughness
8. Melee Weapon Mastery (Slashing)
9. Improved Critical: Greatsword
10. Greater Weapon Focus: Greatsword
12. Greater Weapon Specialization: Greatsword, Improved Sunder
14. Combat Brute
15. Slashing Fury
The character gets a few nifty options with his tactical feats, but generally, just dishes out lots of damage to his enemies.
Another possibility:
Single classed barbarian:
1. Power attack
3. Cleave
6. Weapon Focus
9. Improved Crit
12. Improved Toughness
A little multiclassing can also help this out. The basic mutliclass is Barbarian/Fighter
1. Bbn: Power Atk
2. Bbn 2
3. Bbn 2/Ftr 1: Weapon Focus: Greatsword, Cleave
4. Bbn 2/Ftr 2: Improved Bull Rush
6. Bbn 2/Ftr 4: Weapon Specialization: Greatsword, Extra Rage
8. Bbn 2/Ftr 6: Melee Weapon Mastery slashing
9. Bbn 2/Ftr 7: Shock Trooper
10: Bbn 2/Ftr 8: Greater Weapon Focus: Greatsword
12: Bbn 2/Fighter 10: Imp crit Greatsword, whatever you want
14. Bbn 2/Fighter 12: Greater Weapon Spec. Greatsword
15. Bbn 3/Ftr 12: Slashing Fury
Etc. For a differently flavored fighter, you could start out with 2-5 levels of Knight instead.
You could also reverse the order of the mix and end up Bbn 11/Fighter 4 or Bbn 9/Fighter 6 instead. Or, you could add ranger levels though since you'll probably be wearing heavy armor, they don't do much for you other than skill points and track.
Add in prestige classes, and there's almost an infinite variety of powerful builds, but the barbarian/fighter is probably the one everyone is measured against.