Pandemic "Rage Quitting?"

[Eltab]

I would suggest an one-shot adventure. A little bit gonzo that allows you to suicide PCs if needed and have a backup handy. Sort of like on old convention where the DM handed out PCs and they listed a personality to assist roleplay. You could even design the PCs around another group like Avengers or Scooby Doo. You get to have fun and blow up the game if you like.

Gamma World comes to mind. There was a D&D 4e conversion tucked into a magazine article (don't remember if it was a Dungeon or a Dragon mag), so rules-lite. Intended to be a short campaign with a high chance, just before the end, of finding Ancient tech that can one-hit-KO anything you meet.

 

[MNblockhead]

Try InSPECTREs. Rule light with mechanics that ramp of the social aspects of the game. Good for beer and peanuts, silly, gonzo fun. Sometimes it is nice to play a game where you don't have to fiddle with battlemaps and tokens, look up things in tables, calculate modifiers etc. It is one of the most fun TTRPG that nobody seems to know about.

 

[Fenris-77]

As your doctor, I recommend you use Bubblegumshoe, specifically the Ruby Hollow subset, to run some Scooby Doo shenanigans. Everyone feels better afterwards.