Sex is a recurring theme in my games...along with romance, lovers' quarrels, pregnancies, flings, marriages, creative use of Love Potions, varying sexual preferences, and so on...in no particular order!
Right now in one game I've got three male players playing a mostly-female party (4F, 2M, all PCs) including at least one lesbian. One of the females was male until recently, when a Cloak of Gender Change got him...and that's not the one who's lesbian. And two of the female PCs recently had to deal with a madam trying to recruit them as workers in her brothel. Believe me, that party sometimes gets interesting.
In my other game, we've so far had an unintentional same-sex wedding (result of a wild magic surge, and since annulled by the death of one of those involved), a part-time transvestite, three separate occasions of PCs making out *during combat*, Love Potions used such that two PCs fell hopelessly in love with the same third PC (and *that* got bizarre!). This game has 3 male players and 1 female player running a party about evenly split by gender.
And to give an idea of scale here, all the above examples are from within the past year; the campaign started last March.
Lane-"never a dull moment"-fan