I would like to give kudos to the intent of the 4e designers...
The OP mentioned the comparison to C&C (which is my preferred system), and in one big respect, at least at what is beginning to emerge, there is an apt comparison here.
D&D 4e is attempting a hybridization between "old school" gamist philosophies (the adaptability and less rule-specific mechanics) and the "new school" desires for what the OP refers to in character builds, powers, options etc. (which also focuses away from the traditional archetypes of classes and races to a broader spectrum).
Like C&C, this hybrid approach will likely please some, antagonize others (as it clearly has on these boards). Still, I am not being flip when I say kudos... it takes a bit of risk to go this way, and quite honestly I am somewhat impressed that the larger corporate entity backed what is not as sure a course with the design (of course that may be granting Hasbro execs with more understanding of RPGs than is reality). The fact that TPKs are occurring in playtesting is, for me, a sign that some portions of the game are more like OD&D, B/X, etc.
As I said, I already found my niche with C&C. I've never begrudged those who tried it and didn't like it because a.) It was still too much like d20 in universal mechanics or b.) it is "too" rules-lite --- each to his own niche, I say.
I also think the discussion about battle-maps and minis is very relevent - many on other threads have mentioned the question of "need." While one can make the argument that neither 3.x nor 4e "need" battlemats, from what I've seen the use of "squares" as primary movement indicator shows that 4e is certainly DESIGNED for it. Again, not my cup of tea as it fits more with the "new school" influence of the hybrid here, but for many this may end up being their particular niche.
Of course, the big question that comes up then is -- can we gamers be happy with our system as just a "niche," or are we wanting it to be an "industry standard?"
Since I already play in a niche system, the answer for me is easy.