No way. Not unless you run every pantheon like the ancient greek pantheon.In any sensible setting, gods are pretty much the biggest deal out there.
Standoffish and uncaring gods like Boccob and the Elder Elemental God are IMO a perfectly legitimate and arguably preferable choice to "get thy hands dirty" gods like the FR pantheon during the Time of Troubles, avatars of Bhaal in the Moonshaes, and St Cuthbert, Zagyg and Iuz in Greyhawk.
In fact, it could be argued that interventional deities are worse, because they present a dilemma comparable to FR's high level NPCs. "Why doesn't Elminster solve it?" becomes "Why doesn't Bahamut solve it?" if you can run into Bahamut and tip your hat to him on the way to the shops.
I much prefer a bottom-up approach, where the opinion of the innkeeper that the PCs are thugs has a lot more impact on the campaign than the opinion of some greater god, if he ever deigned to notice the PCs.
But we're talking about gods again, and they're flat out boring. Why can't we talk about something IMPORTANT to FR, like are there still mad archmages and senile liches, ancient weird magic floating around just for the flavour of it, the romantic doomed adventurers joshing around a campfire vibe, hints of arcane mysteries from long ago...you know, the stuff that makes FR, FR?
That's the stuff that's easy to get wrong.
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