Well, they were originally 4HD. So how about CR 4 or 5?

As I suggested upthread, I'd favor flavor text talking about the effect on elder brains. If you really want mechanics, what about some disease with a high Fort DC that only infects brain matter?
Do elder brains have a level adjustment? If I remember, I might just have to check that tonight.![]()

No need for the jar, they have a 30 ft fly speed. They don't actually have an LA line in their stat block, though the other monsters in Lords of Madness do. I suspect it's supposed to be LA: -, though.
I don't know, I find something appealing about a 10-ft-diameter levitating glowing brain.![]()

Here's a start:
Purple Lichen (CR 5?)
Purple lichen, technically a fungus rather than a lichen, is a psionic parasite that grows in thin layers on underground floors, walls and ceilings. Any psionic creature within 10 feet of a patch of purple lichen must make a DC X Will save or lose Y power points. For each Z points the lichen patch drains, it grows to fill an additional 5 ft square. It is rumored that renegade mind flayers developed purple lichen to attack elder brains; some scholar speculate that purple lichen causes a horrific disease when placed in direct contact with brain matter.
A 5-ft square patch of purple lichen has 10? hit points but is immune to weapon damage. Purple lichen is rendered dormant by exposure to any bright light, and it is killed instantly by exposure to natural daylight or a daylight spell.

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.