Only one PC I've played really has an actor that easily comes to mind without pushing a square peg into a round hole.
Jhomp - CG half-orc barbarian who's really a decent guy but "just doesn't know any better" when it comes to tact. Once helped some refugees escape capture by city guards through use of what has become known as the Milk And Porkchops Gambit. Easily amused.
Adam Baldwin all the way.
Almost got to play an elf sniper in a Shadowrun game once before my schedule got in the way. There was no way he could be played by anyone other than Annie Lennox, the way things were working out. Elves, eh?