Fair enough. I'd say that pretty much applies to most settings....don't you? Like I said...are the differences between Oerth, Mystara, Golarion, and the Realms really that different? Can't the Scarlet Brotherhood be moved over to the Realms with ease? Can't the Circle of Eight or Castle Greyhawk?
Then there's always the question of what a DM does with the source material. Maybe one DM can take a bog standard fantasy trope and do somethib really cool with it for his game, while another may need all the coolness baked in without any ability to add his own.
Sure, Chult seems like many other jungle settings. So do Xen'drik, the Amedio Jungle, the Mwangi Expanse...and so on. And likely the jungles of 98% of home brewed worlds. I mean...it's a jungle, how unique are they? One's got dinosaurs and the other's got drow and the other has Aztecs....and all could be shuffled among their various home settings with little disruption to the rest of it.
As for the trade routes and roads...it seems an odd reason to dismiss a setting, to me, but okay. I don't know if I've ever looked at a fantasy setting map and thought to myself "now there are some verisimilitudinous trade routes, by George", but to each his own.
Don't be silly....the Greyhawk NPC that trapped NINE gods wasn't Mordenkainen, it was Zagyg.