Wil Wheaton and guests Ed Brubaker (Writer—Captain America, Criminal, Angel of Death), Robert Gifford (Founder—Geek Chic), and Morgan Webb (Host—X-Play) play Pandemic over on Geek & Sundry's latest episode of Tabletop. Pandemic is a cooperative board game designed by Matt Leacock and published by Z-Man Games in 2008, based on the premise that four diseases have broken out in the world, each threatening to wipe out a region. The game accommodates 2 to 4 players, each playing one of five possible specialists: (dispatcher, medic, scientist, researcher or operations expert). The game is unlike most boardgames as the gameplay is cooperative, rather than competitive. Through the combined effort of all the players, the goal is to discover all four cures before any of several game-losing conditions are reached.
Wil Wheaton's web series Tabletop featured an interview with Steve Jackson in the latest episode. The episode itself also featured Felicia Day and and Sandeep Parikh and looked at Jackson's card game, Munchkin. The show mainly deals with board games, but the occasional RPG mentions pop up from time to time, like now. You can find out more about Tabletop over at Felicia Day's GeekandSundry.