You're unlikely to see one that makes it to the "mainstream" following you'd like to see. Trek managed to make it work by jumping over current events of the time. If you want to discuss what good we can do by 30 or 40 years from now, you have to address current problems - and that makes your show political. Probably very political.
One current sci-fi tv show which does this in a clever manner, is Continuum.
http://en.wikipedia.org/wiki/Continuum_(TV_series)