D&D and the rising pandemic

[FrogReaver]

Decline in influenza vaccine effectiveness with time after vaccination, Navarre, Spain, season 2011/12 - PubMed

This study evaluates the influenza vaccine effectiveness (VE) in preventing laboratory-confirmed cases in Navarre, Spain, in the 2011/12 season in which the peak was delayed until week 7 of 2012. We conducted a test-negative case–control study. Patients with influenza-like illness in hospitals...

www.ncbi.nlm.nih.gov

The timeframe was <100 days and the geographical position was unchanged. I.e. same strains prevalent.

The first article states: "Most characterized viruses did not match the vaccine strains." That's contrary to your assertion above. I see no evidence in that article of whether the vaccine was less effective due to fewer antibodies over time or due to other flu strains prevalent in the area.

And another: Waning vaccine protection against influenza A (H3N2) illness in children and older adults during a single season. - PubMed - NCBI

ETA: I have no idea how I quoted an old message initially. Fixed it.

This article also doesn't note whether it's a different strain of influenza A that infected people later in the season than the vaccine was designed to prevent.

Do you have any evidence that actually supports your conclusion. I find the premise fascinating but I've seen nothing in those articles or anywhere else to confirm it.

 

[Eltab]

I was out yesterday and saw a guy with a beard who had the mask covering the beard, but not his nose and mouth. I guess the beard was sick and needed the restriction more than he did?

"I gotta find a barber to fix this, how embarrassing"

 

[Nagol]

The first article states: "Most characterized viruses did not match the vaccine strains." That's contrary to your assertion above. I see no evidence in that article of whether the vaccine was less effective due to fewer antibodies over time or due to other flu strains prevalent in the area.



This article also doesn't note whether it's a different strain of influenza A that infected people later in the season than the vaccine was designed to prevent.

Do you have any evidence that actually supports your conclusion. I find the premise fascinating but I've seen nothing in those articles or anywhere else to confirm it.

I'm not going to keep digging through scholarly articles. Feel free to do your own research.

Immunization Action Coalition says:
How long does immunity from influenza vaccine last?
Protection from influenza vaccine is thought to persist for at least 6 months. Protection declines over time because of waning antibody levels and because of changes in circulating influenza viruses from year to year. For persons who require only 1 dose of influenza vaccine for the season, yearly vaccination (i.e. in July and August) is likely to be associated with suboptimal immunity before the end of the influenza season, particularly among older adults.

 

[FrogReaver]

I'm not going to dig through the scholarly articles. Feel free to do your own research.

You were the one with the assertion.

Here's what the CDC says:
How long does immunity from influenza vaccine last?
Protection from influenza vaccine is thought to persist for at least 6 months. Protection declines over time because of waning antibody levels and because of changes in circulating influenza viruses from year to year. For persons who require only 1 dose of influenza vaccine for the season, yearly vaccination (i.e. in July and August) is likely to be associated with suboptimal immunity before the end of the influenza season, particularly among older adults.

I was able to finally find my answer on google. Vaccination and antibodies - myDr.com.au

I think this article explains it very well. Antibodies last weeks. Memory B Cells last much longer (typically). When a Memory B Cell detects the virus again the immune response is much quicker which leads to a much better outcome - thus the reason for potentially lifetime immunity to many viruses.

Why does anyone think our typical immune response to covid-19 will be particularly different than normal? Why will Memory B cells not identify the virus and have the immune system spring into action and protect us for a long time to come? That's the science part of this discussion I don't get. I mean I get that it's not proven they will - but there's also nothing to suggest anything about this virus will be vastly different from pretty much every other virus we have ever encountered.

Also of note is that the CDC quote you supplied agrees with me, that VE is a combination of antibodies and virus mutations. It never says which is actually the cause of VE declining for the flu in 6 months.

 

[FrogReaver]

On a side note: Is anyone else missing the report a post option?

An example of my screen: (not that I intended to report this post - just an example)

 

[ccs]

The White House Press Corps does that on a daily basis. For 45 minutes, in one instance.

Yeah and they get any # of different answers, snark, crap that doesn't apply to anything, etc. It's like pulling the lever on a slot machine.

 

[FrogReaver]

Yeah and they get any # of different answers, snark, crap that doesn't apply to anything, etc. It's like pulling the lever on a slot machine.

They could actually ask better questions most the time. #DeclineOfJournalism

 

[Theo R Cwithin]

Why does anyone think our typical immune response to covid-19 will be particularly different than normal? Why will Memory B cells not identify the virus and have the immune system spring into action and protect us for a long time to come? That's the science part of this discussion I don't get.

I don't think people believe covid-19 necessarily is different. It's just that docs don't know yet, for lack of data. That's the science in action, right now. It's simply too early to tell... hence the great caution.

but there's also nothing to suggest anything about this virus will be vastly different from pretty much every other virus we have ever encountered.

My understanding is that there is a fair bit of worry that this virus could be a bit nastier than many others. Apparently doctors are seeing that it impacts quite a few of the body's system aside from the lungs, including heart, kidneys, and brain-- even toes. Here's a pretty comprehensive overview of current understanding, about a week old:

Science | AAAS

www.sciencemag.org

 

[Eltab]

Yeah and they get any # of different answers, snark, crap that doesn't apply to anything, etc. It's like pulling the lever on a slot machine.

I think with each Presidential election, not only the occupant of the White House but the individuals who get Press passes inside should change. I am positive there are more than just 30 journalists who could hold down that job.

For instance having Jim Cramer, who made his career in and around the stock market (and also has journalist experience), asking about the economy would offer meaningful questions that DC Desk Larry would never think of.

 

[Dannyalcatraz]

On a side note: Is anyone else missing the report a post option?

You might want to PM Morrus.