The Crimson Binome
Hero
YMMV, of course. In my experience, most saving throws made by a high-level party will be successful. With all of the different ways to gain advantage, a Paladin aura granting +5 to all saves for everyone, and bless adding +1d4 to help normalize the probability distribution; yeah, an AoE save-for-none against the group will average significantly less damage than just attacking twice.Not sure if I understand. Are you saying that all PCs can make a DC 22 Dex save vs an Adult Red Dragon's Wing Attack at will? Not in my experience.
The other possibility is that it will affect one PC, who will be knocked down, and who will stand up again before the dragon's next turn.