In our home game, one of the players (who does not post here) was absent one day. This was about two years ago, and we weren't very high level yet.
During a battle, the evil cleric cast Random Action on him and he crit'ed himself. Being a dwarven barbarian, he survived. But at the end of the battle, the evil cleric threw down a bead from a Necklace of Fireballs and that spelled doom for our little friend.
To add insult to injury, the player wasn't there that day--the day his character died, partially by his own hand.