My group gamed under a female GM several times. *All* her NPCs were bitter and taciturn (even the ones that we were supposed to like). She was more into free-form games "Ok, where do you want to go today?" rather than "You are hired by lord ..." Very cool concept that could be very rewarding if it was pulled off correctly, unfortunately it wasn't. If only I could get back those Saturdays of 8-hour sessions of repeated failures (and the game title did not even contain the word Cthulhu!).
GM: "Well, you chose to leave the city, so you get attacked by three griffons just outside the front gate. If you stayed in town instead and worked on the mural for the week or farmed for the week instead of trying to go on an adventure, you might have been able to get some gold."
Players: wooo.... Yes, farming is the ultimate goal for mages/warriors/rogues.
Bitter? Who, me?
Ok, so it was an exaggeration. It was one griffon, not three. And we were level 2 at the time. After three weeks of playing 6-8 hour sessions.
We aaaaalmost had another female GM, but she backed out. She was going to run an elf-focused, romance-focused game. She was one of those really rare ballerina, kitty cats, pink frilly dress-type girls who play D&D. She was a good player, a good role-player, and I think that her campaign could have been fun. I, of course, would have to play the surly dwarf. But all in good fun.