Yaarel
🇮🇱 🇺🇦 He-Mage
Yeah. The most stunning example was when someone used a 4e Monk for its unarmed combat to mechanically play a bear. It worked well.You can get pretty far just with that, almost to the point of not being recognizable as D&D. I made a homebrew setting where every PHB class, subclass, race, and background were refluffed but all mechanics other than name and description of abilities kept intact verbatim.
4e is designed for easy reflavoring. 5e bakes narrative into the mechanics, so is sometimes prohibitively difficult depending on what narrative one is trying build.