I used much of the stuff from DS in my D&D game, which is (in part) inspired by Star Ocean. (And I crashed the ship from Raw Recruits into my world)
Works much better than d20 Modern/Future. (though that perhaps isn't saying much, IMHO, since the more I play d20 Modern, the more I despise it)
(Though bear in mind, what I really mean is that Dragonstar's basic premise is D&D in space/future. It does a much better job of it than d20 Modern ever could, since d20 Modern is not D&D in modern times. There are no Paladins, Rangers, Clerics, Sorcerers, etc in d20 Modern, nor is there magic items up the wazoo. d20 Modern starts off being basically a somewhat cinematic version of the real world, though this branches out towards fantasy in Urban Arcana.
While I really dislike the implementation of d20 Modern, even if it were done better (closer to Spycraft), it would still be wrong for Dragonstar for the above reason)