I doubt it would work for me. My aesthetic in gaming is to have multiple minigames that are highly specific to the task resolution that they are trying to simulate. So I would want a combat system granular enough to handle everything from sharpened sticks to automatic weapons and "phased plasma rifle in a 40 terawatt range" and so forth while giving each weapon a distinctive feel. Travel would be an important part of the game and so I'd want something that could handle the difference between bitter cold, acid rain, and a radioactive ash storm. Having everything just be a generic test with generic consequences doesn't cut it for me, and I just don't trust something as generic as Cortex Prime to deal with that. And I'd be drawing on inspiration as diverse as "A Canticle for Leibowitz" and "Mad Max", and of course "Hiero's Journey" (the inspiration for Gamma World).