I intensely dislike random elements in character generation, be it HP, ability scores, or whatever. It better be a helluva DM, and I better roll well, otherwise, no thanks.
No level drain under any circumstances. Ever.
I'll never DM 2e, or 3e (or any derivative thereof like Pathfinder). But I'll play if the DM is awesome and they houserule out random chargen and level drain.
So, in short, there is probably nothing I wouldn't play, but I would try to steer clear of the following if I could:
- Warhammer 40k tabletop (and other miniature games, but I love RPGs based on some of these)
And lastly, just to throw some stuff out there that I would love the opportunity to play again if I could only find some players:
- Bloodbowl
It's odd that you aren't interested in miniatures games but really want to play a miniatures game that has a board grafted onto it.
Unless you are talking about the financial aspect of minis gaming, which is pretty much why I stopped playing 40k soon after 3rd edition rolled out.
DS

(Dungeons & Dragons)
Rulebook featuring "high magic" options, including a host of new spells.