I remember an Israeli pharmaceutical researcher was doing some really important work on potential uses for the chemicals in marijuana back in the 1990s. When he was asked about the American medical marijuana movement, he laughed his ass right off.
(Seriously, the “thump” was audible, even over his laughter.)
His point was very much along those lines. The dosage of THC (and everything else) was impossible to control when sold in leafy form, whit countless varietals on the market. He dismissed the activists’ efforts as people who just wanted to get stoned.
And this was a man who had great expectations for using marijuana-derived products in legitimate medical practice around the world.
Side note: the dosage issue has cropped up again in the domain of medical or supplemental gummy products. Research has shown dosages can vary greatly from gummy to gummy, as a result of how they’re made. No such problems exist with pills, capsules or gelcaps.