Oh, yeah. At least at low levels, my Genasi blaster mage really brings on the pain -- using wizard and Genasi features for striker mobility, Flaming Sphere (at 5th level, twice per day using a Tome of Replenishing Flame unless I -need- my other daily) to simply win encounters (and to let me get serious single-target damage; for when big, sometimes party friendly huge damage area spells aren't enough), and even the occasional control effect. The nice thing about blaster wizards is that you don't -have- to avoid actual control to be a blaster (and, in fact, true wizard control in the at will slots is fairly weak, but that's ok because you control with your dailies); you can still take the top-of-tier lockdown spells when they show up and use your at wills to drop enlarged Scorching (now Freezing) Burst on piles of the enemy, which huge effective accuracy (because when you're targetting 5 monters, your "I got a bad roll" is still outdamaging Twin Strike).
For that matter, -every- wizard can, starting at first level, dip a secondary striker roll just by taking Flaming Sphere--which is still the top-of-grade spell at that level. For one encounter per day, your single target DPR becomes 1d4+int+implement+bonuses+hit%(2d6+int+implement+bonuses) (so at level 1, with a +1 implement and a 55% hit chance (low), 15.65) -- what are you complaining about again?