For me it would depend on the setup. If the adventure says, "The chest is covered in contact poison. Anyone trying to open it must make a Con save..." then gloves aren't the issue.
More important to me would be the process of how we got here. Were there rolls to notice the poison that failed? Was the player careful or hasty?
One of the problem with using traps like this is it put the onus on the GM to convey the important information. Which invariably slows the game down. As soon as you say, "HOW are you opening the chest?" everything grinds to a halt. There are better ways to adjust the risk/reward ratio.
More important to me would be the process of how we got here. Were there rolls to notice the poison that failed? Was the player careful or hasty?
One of the problem with using traps like this is it put the onus on the GM to convey the important information. Which invariably slows the game down. As soon as you say, "HOW are you opening the chest?" everything grinds to a halt. There are better ways to adjust the risk/reward ratio.