I'm likely with the minority in that I didn't "grow up" with D&D. In my first 25 years of roleplaying, I played a single AD&D campaign (Al Quadim) that lasted maybe 3-6 months. I've played dozens of other RPGs during that time, instead.
And then when 5E came out, we tried it out, and found it much more comfortable to work with than earlier editions. And one friend who was part of that, a brand new player and thus getting his first experience in RPGs with D&D 5E, decided that D&D was everything, and has used it to run several years' worth of games since then. So in that sense, 5E is the version of D&D that I've spent the most time playing.
He's still in the baby GM stage, though, where he's trying to modify D&D to be something different, but hasn't really grokked that other games exist (aside from Pathfinder), and that many are better suited to what he wants to do.