I'm planning on picking up the core books; probably the FR campaign book. Beyond that, I'm not planning on buying or playing. I've been looking at alternative rulesystems, and will probably switch to True20. I like it, I can convert now, and the cost for my players to buy in is alot less than D&D.
The mechanics of 4e aren't a big deal for me, but it's another straw on the camel. I'm mid-30's, I'm too invested in 3e to throw out thousands of dollars worth of books, WOtC is ditching the OGL, and I'm just tired of the constant turnover in the game. I want to work on my setting with a relatively simple set of rules that I can customize to my taste.
Also, the OGL is a big deal to me.